The following is my log. The machine has become unstable with many symptoms (slow/no loading, failure to shut down, etc.). I've done virus scans with Trend Micro (new version), Ewido, and Spybot. Problems persist. Any and all help would be much appreciated. Also, since I'm faithfully running Trend Micro, Ewido, Spybot and Webroot how is it that something slipped through? I thought I was pretty safe with all this anti-virus stuff running.
Logs follow:

Logfile of HijackThis v1.99.1
Scan saved at 11:35:59 AM, on 11/20/2006
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\ewido\security suite\ewidoctrl.exe
C:\PROGRA~1\TRENDM~1\INTERN~4\PcCtlCom.exe
C:\WINDOWS\System32\svchost.exe
C:\PROGRA~1\TRENDM~1\INTERN~4\Tmntsrv.exe
C:\PROGRA~1\TRENDM~1\INTERN~4\TmPfw.exe
C:\Program Files\Webroot\Spy Sweeper\SpySweeper.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\System32\hkcmd.exe
C:\WINDOWS\System32\LVCOMSX.EXE
C:\Program Files\Logitech\Video\LogiTray.exe
C:\Program Files\Webroot\Spy Sweeper\SpySweeperUI.exe
C:\WINDOWS\system32\spool\drivers\w32x86\3\hpztsb09.exe
C:\Program Files\HP\hpcoretech\hpcmpmgr.exe
C:\WINDOWS\system32\hphmon05.exe
C:\Program Files\Hewlett-Packard\HP Software Update\HPWuSchd2.exe
C:\Program Files\Java\jre1.5.0_09\bin\jusched.exe
C:\Program Files\QuickTime\qttask.exe
C:\PROGRA~1\TRENDM~1\INTERN~4\pccguide.exe
C:\Program Files\Messenger\msmsgs.exe
C:\Program Files\Google\GoogleToolbarNotifier\1.2.908.5008\GoogleToolbarNotifier.exe
C:\Program Files\Trend Micro\Internet Security 2007\TMAS_OE\TMAS_OEMon.exe
C:\Program Files\Adobe\Acrobat 6.0\Distillr\acrotray.exe
C:\Program Files\Logitech\Video\FxSvr2.exe
C:\Program Files\Intel\Intel® Active Monitor\imonnt.exe
C:\Program Files\Webroot\Spy Sweeper\SSU.EXE
C:\WINDOWS\system32\wscntfy.exe
C:\WINDOWS\system32\HPZipm12.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\PROGRA~1\TRENDM~1\INTERN~4\tmproxy.exe
C:\Program Files\Outlook Express\msimn.exe
C:\Program Files\Trend Micro\Internet Security 2007\TMAS_OE\TMAS_OE.exe
C:\HJT\Analyze.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://norcalmls.rapmls.com/
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 6.0\Acrobat\ActiveX\AcroIEHelper.dll
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.5.0_09\bin\ssv.dll
O2 - BHO: Google Toolbar Helper - {AA58ED58-01DD-4d91-8333-CF10577473F7} - c:\program files\google\googletoolbar2.dll
O2 - BHO: AcroIEToolbarHelper Class - {AE7CD045-E861-484f-8273-0445EE161910} - C:\Program Files\Adobe\Acrobat 6.0\Acrobat\AcroIEFavClient.dll
O3 - Toolbar: Adobe PDF - {47833539-D0C5-4125-9FA8-0819E2EAAC93} - C:\Program Files\Adobe\Acrobat 6.0\Acrobat\AcroIEFavClient.dll
O3 - Toolbar: &Google - {2318C2B1-4965-11d4-9B18-009027A5CD4F} - c:\program files\google\googletoolbar2.dll
O4 - HKLM\..\Run: [HotKeysCmds] C:\WINDOWS\System32\hkcmd.exe
O4 - HKLM\..\Run: [LVCOMSX] C:\WINDOWS\System32\LVCOMSX.EXE
O4 - HKLM\..\Run: [LogitechVideoRepair] "C:\Program Files\Logitech\Video\ISStart.exe"
O4 - HKLM\..\Run: [LogitechVideoTray] "C:\Program Files\Logitech\Video\LogiTray.exe"
O4 - HKLM\..\Run: [SpySweeper] "C:\Program Files\Webroot\Spy Sweeper\SpySweeperUI.exe" /startintray
O4 - HKLM\..\Run: [HPDJ Taskbar Utility] C:\WINDOWS\system32\spool\drivers\w32x86\3\hpztsb09.exe
O4 - HKLM\..\Run: [HPHUPD05] "c:\Program Files\Hewlett-Packard\\{5372B9A6-6E51-4f90-9B40-E0A3B8475C4E}\hphupd05.exe"
O4 - HKLM\..\Run: [HP Component Manager] "C:\Program Files\HP\hpcoretech\hpcmpmgr.exe"
O4 - HKLM\..\Run: [HPHmon05] C:\WINDOWS\system32\hphmon05.exe
O4 - HKLM\..\Run: [HP Software Update] "C:\Program Files\Hewlett-Packard\HP Software Update\HPWuSchd2.exe"
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files\Java\jre1.5.0_09\bin\jusched.exe"
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [pccguide.exe] C:\PROGRA~1\TRENDM~1\INTERN~4\pccguide.exe
O4 - HKCU\..\Run: [MSMSGS] "C:\Program Files\Messenger\msmsgs.exe" /background
O4 - HKCU\..\Run: [swg] "C:\Program Files\Google\GoogleToolbarNotifier\1.2.908.5008\GoogleToolbarNotifier.exe"
O4 - HKCU\..\Run: [OE] "C:\Program Files\Trend Micro\Internet Security 2007\TMAS_OE\TMAS_OEMon.exe"
O4 - Global Startup: Acrobat Assistant.lnk = C:\Program Files\Adobe\Acrobat 6.0\Distillr\acrotray.exe
O4 - Global Startup: Adobe Reader Speed Launch.lnk = C:\Program Files\Adobe\Acrobat 7.0\Reader\reader_sl.exe
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.5.0_09\bin\ssv.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.5.0_09\bin\ssv.dll
O12 - Plugin for .spop: C:\Program Files\Internet Explorer\Plugins\NPDocBox.dll
O15 - Trusted Zone: http://www.aapsma.com
O15 - Trusted Zone: *.agencycircle.com
O15 - Trusted Zone: *.agencycircle.net
O15 - Trusted Zone: *.agencycircle.org
O15 - Trusted Zone: *.c21alliance.com
O15 - Trusted Zone: http://*.c21conference.com
O15 - Trusted Zone: www.benefits.ehr.com
O15 - Trusted Zone: *.enom.com
O15 - Trusted Zone: *.godaddy.com
O15 - Trusted Zone: *.instantgift.com
O15 - Trusted Zone: *.kayandbill.com
O15 - Trusted Zone: http://*.match.com
O15 - Trusted Zone: *.point2agent.biz
O15 - Trusted Zone: *.point2agent.com
O15 - Trusted Zone: http://*.rapmls.com
O15 - Trusted Zone: *.realist.com
O15 - Trusted Zone: *.realtor.org
O15 - Trusted Zone: *.reil.com
O15 - Trusted Zone: *.sfarmls.com
O15 - Trusted Zone: http://*.snbank.com
O15 - Trusted Zone: http://www.suttersantarosa.org
O15 - Trusted Zone: https://*.webconference.com
O15 - Trusted Zone: http://download.windowsupdate.com
O15 - Trusted Zone: *.wyldfyreweb.com
O15 - Trusted IP range: 209.204.140.191
O16 - DPF: PUFLITE - http://billzane.point2agent.com/Office/Col…rol/PUFLITE.CAB
O16 - DPF: {17492023-C23A-453E-A040-C7C580BBF700} (Windows Genuine Advantage Validation Tool) - http://go.microsoft.com/fwlink/?linkid=39204
O17 - HKLM\System\CCS\Services\Tcpip\..\{948EF5AB-5846-475A-AFDE-E5492D4BAC89}: NameServer = 209.204.187.9,209.204.187.14
O20 - Winlogon Notify: igfxcui - C:\WINDOWS\SYSTEM32\igfxsrvc.dll
O20 - Winlogon Notify: WgaLogon - C:\WINDOWS\SYSTEM32\WgaLogon.dll
O20 - Winlogon Notify: WRNotifier - C:\WINDOWS\SYSTEM32\WRLogonNTF.dll
O23 - Service: ewido security suite control - ewido networks - C:\Program Files\ewido\security suite\ewidoctrl.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\11\Intel 32\IDriverT.exe
O23 - Service: IMAPI CD-Burning COM Service (ImapiService) - Roxio Inc. - C:\WINDOWS\System32\ImapiRox.exe
O23 - Service: Intel® Active Monitor (imonNT) - Intel Corp. - C:\Program Files\Intel\Intel® Active Monitor\imonnt.exe
O23 - Service: iPodService - Apple Computer, Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: Macromedia Licensing Service - Unknown owner - C:\Program Files\Common Files\Macromedia Shared\Service\Macromedia Licensing.exe
O23 - Service: Intel® NMS (NMSSvc) - Intel Corporation - C:\WINDOWS\System32\NMSSvc.exe
O23 - Service: Trend Micro Central Control Component (PcCtlCom) - Trend Micro Inc. - C:\PROGRA~1\TRENDM~1\INTERN~4\PcCtlCom.exe
O23 - Service: Trend Micro Protection Against Spyware (PcScnSrv) - Trend Micro Inc. - C:\PROGRA~1\TRENDM~1\INTERN~4\PcScnSrv.exe
O23 - Service: Pml Driver HPZ12 - HP - C:\WINDOWS\system32\HPZipm12.exe
O23 - Service: Trend Micro Real-time Service (Tmntsrv) - Trend Micro Inc. - C:\PROGRA~1\TRENDM~1\INTERN~4\Tmntsrv.exe
O23 - Service: Trend Micro Personal Firewall (TmPfw) - Trend Micro Inc. - C:\PROGRA~1\TRENDM~1\INTERN~4\TmPfw.exe
O23 - Service: Trend Micro Proxy Service (tmproxy) - Trend Micro Inc. - C:\PROGRA~1\TRENDM~1\INTERN~4\tmproxy.exe
O23 - Service: Webroot Spy Sweeper Engine (WebrootSpySweeperService) - Webroot Software, Inc. - C:\Program Files\Webroot\Spy Sweeper\SpySweeper.exe