alsocom
Glad to hear that it worked in Safe Mode. 
I'll give you some optional items to fix that are known to slow down a computer.
Open HijackThis, run a scan, then check the following:
Optional items to check with HijackThis for improved performance.
You have Microsoft's Find Fast running on your PC and while a legitimate program, it is a resource hog. It is usually the cause of your computer getting really slow or even freezing for several seconds while it is indexing. Find fast neither finds things any better or faster than other Windows searches. You will notice system improvement by disabling this one. Go into the FindFast icon in the Control Panel and choose the "Index \ Close and Stop" menu option.
O4 - Startup: Microsoft Find Fast.lnk = C:\Program Files\Microsoft Office\Office\FINDFAST.EXE
Resource hog that launches common MS Office components to help speed up the launch of Office programs. Some users claim there's no difference with or without it but it isn't required either way.
O4 - Startup: Office Startup.lnk = C:\Program Files\Microsoft Office\Office\OSA.EXE
With all other programs and browsers closed, click fix checked.
I would like to see one more HijackThis log, after the computer has been rebooted a few times, just to make sure the infection does not return.
I'll give you some optional items to fix that are known to slow down a computer.
Open HijackThis, run a scan, then check the following:
Optional items to check with HijackThis for improved performance.
You have Microsoft's Find Fast running on your PC and while a legitimate program, it is a resource hog. It is usually the cause of your computer getting really slow or even freezing for several seconds while it is indexing. Find fast neither finds things any better or faster than other Windows searches. You will notice system improvement by disabling this one. Go into the FindFast icon in the Control Panel and choose the "Index \ Close and Stop" menu option.
O4 - Startup: Microsoft Find Fast.lnk = C:\Program Files\Microsoft Office\Office\FINDFAST.EXE
Resource hog that launches common MS Office components to help speed up the launch of Office programs. Some users claim there's no difference with or without it but it isn't required either way.
O4 - Startup: Office Startup.lnk = C:\Program Files\Microsoft Office\Office\OSA.EXE
With all other programs and browsers closed, click fix checked.
I would like to see one more HijackThis log, after the computer has been rebooted a few times, just to make sure the infection does not return.