Programs result in "not responding"

WinXP Pro Dell Dimension 8300 2.5 gigs memory

My programs stop responding, some immediately, others like Opera after a short time. I cannot close them, terminate them. It requires a reboot. Programs load VERY slowly, even from startup. I canno teven get to a "restore"; nothing happens when I click on wiondow for this. Some programs never show up when I try to start them.

Hijack log:

Logfile of HijackThis v1.99.1
Scan saved at 8:34:05 PM, on 3/4/2008
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v7.00 (7.00.6000.16608)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Ahead\InCD\InCDsrv.exe
C:\Program Files\Lavasoft\Ad-Aware 2007\aawservice.exe
C:\Program Files\Avast4\aswUpdSv.exe
C:\Program Files\Avast4\ashServ.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\system32\WDBtnMgr.exe
C:\Program Files\Microsoft AntiSpyware\gcasDtServ.exe
C:\Program Files\Logitech\MouseWare\system\em_exec.exe
C:\Program Files\COMODO\Firewall\cmdagent.exe
C:\WINDOWS\System32\CTsvcCDA.exe
C:\Program Files\Diskeeper\DkService.exe
C:\PROGRA~1\Iomega\System32\AppServices.exe
C:\WINDOWS\system32\nvsvc32.exe
C:\Program Files\Dantz\Retrospect\retrorun.exe
C:\PROGRA~1\Dantz\RETROS~1\wdsvc.exe
C:\Program Files\Photodex\ProShowGold\ScsiAccess.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\System32\MsPMSPSv.exe
C:\Program Files\Iomega\AutoDisk\ADService.exe
C:\Program Files\Canon\CAL\CALMAIN.exe
C:\Program Files\Avast4\ashMaiSv.exe
C:\Program Files\Avast4\ashWebSv.exe
C:\PROGRA~1\Avast4\ashDisp.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\COMODO\Firewall\cfp.exe
C:\Program Files\AIM\aim.exe
C:\Program Files\EverNote\EverNote\UniClipper.exe
C:\Program Files\Eraser\Eraser.exe
C:\Program Files\StickyPad\StickyPad.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\Adobe\Acrobat 6.0\Distillr\acrotray.exe
C:\Program Files\Eudora\Eudora.exe
C:\Program Files\Opera\Opera.exe
C:\Program Files\Hijackthis\HijackThis.exe

R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R3 - URLSearchHook: Yahoo! Toolbar - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - C:\Program Files\Yahoo!\Companion\Installs\cpn\yt.dll
O2 - BHO: Yahoo! Toolbar Helper - {02478D38-C3F9-4EFB-9B51-7695ECA05670} - C:\Program Files\Yahoo!\Companion\Installs\cpn\yt.dll
O2 - BHO: Adobe PDF Reader Link Helper - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEHelper.dll
O2 - BHO: COmeaHelper Object - {09628AAA-66AD-4FA2-82E2-698185B66463} - C:\Program Files\JetBrains\Omea Reader\IexploreOmeaW.dll
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\Spybot\SDHelper.dll
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.6.0_03\bin\ssv.dll
O2 - BHO: Google Toolbar Helper - {AA58ED58-01DD-4d91-8333-CF10577473F7} - c:\program files\google\googletoolbar5.dll
O2 - BHO: AcroIEToolbarHelper Class - {AE7CD045-E861-484f-8273-0445EE161910} - C:\Program Files\Adobe\Acrobat 6.0\Acrobat\AcroIEFavClient.dll
O3 - Toolbar: Adobe PDF - {47833539-D0C5-4125-9FA8-0819E2EAAC93} - C:\Program Files\Adobe\Acrobat 6.0\Acrobat\AcroIEFavClient.dll
O3 - Toolbar: Omea - {35402C01-1777-4159-9ABA-3480BA70D90A} - C:\Program Files\JetBrains\Omea Reader\IexploreOmeaW.dll
O3 - Toolbar: &Google - {2318C2B1-4965-11d4-9B18-009027A5CD4F} - c:\program files\google\googletoolbar5.dll
O3 - Toolbar: Yahoo! Toolbar - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - C:\Program Files\Yahoo!\Companion\Installs\cpn\yt.dll
O4 - HKLM\..\Run: [DeadAIM] rundll32.exe "C:\PROGRA~1\AIM\\DeadAIM.ocm",ExportedCheckODLs
O4 - HKLM\..\Run: [WD Button Manager] WDBtnMgr.exe
O4 - HKLM\..\Run: [Logitech Utility] Logi_MwX.Exe
O4 - HKLM\..\Run: [gcasServ] "C:\Program Files\Microsoft AntiSpyware\gcasServ.exe"
O4 - HKLM\..\Run: [NeroFilterCheck] C:\WINDOWS\system32\NeroCheck.exe
O4 - HKLM\..\Run: [avast!] C:\PROGRA~1\Avast4\ashDisp.exe
O4 - HKLM\..\Run: [KernelFaultCheck] %systemroot%\system32\dumprep 0 -k
O4 - HKLM\..\Run: [COMODO Firewall Pro] "C:\Program Files\COMODO\Firewall\cfp.exe" -s
O4 - HKLM\..\Run: [Adobe Reader Speed Launcher] "C:\Program Files\Adobe\Reader 8.0\Reader\Reader_sl.exe"
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE C:\WINDOWS\system32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKCU\..\Run: [AIM] C:\Program Files\AIM\aim.exe -cnetwait.odl
O4 - HKCU\..\Run: [UniClipper] "C:\Program Files\EverNote\EverNote\UniClipper.exe"
O4 - HKCU\..\Run: [Eraser] C:\Program Files\Eraser\Eraser.exe -hide
O4 - HKCU\..\Run: [Sticky Pad] C:\Program Files\StickyPad\StickyPad.exe
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - HKCU\..\RunOnce: [] C:\Program Files\Internet Explorer\IEXPLORE.EXE http://www.symantec.com/techsupp/servlet/P…000021.0000004d
O4 - Global Startup: Acrobat Assistant.lnk = C:\Program Files\Adobe\Acrobat 6.0\Distillr\acrotray.exe
O6 - HKCU\Software\Policies\Microsoft\Internet Explorer\Control Panel present
O8 - Extra context menu item: &AIM Search - res://C:\Program Files\AIM Toolbar\AIMBar.dll/aimsearch.htm
O8 - Extra context menu item: &NeoTrace It! - C:\PROGRA~1\NEOTRA~1\NTXcontext.htm
O8 - Extra context menu item: &Spurl! - http://www.spurl.net/rclick.php
O8 - Extra context menu item: Add to EverNote - res://C:\Program Files\EverNote\EverNote\enbar.dll/2000
O8 - Extra context menu item: Clip and Edit - res://C:\Program Files\JetBrains\Omea Reader\IexploreOmeaW.dll/1000
O8 - Extra context menu item: Clip and Save - res://C:\Program Files\JetBrains\Omea Reader\IexploreOmeaW.dll/1001
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~4\Office10\EXCEL.EXE/3000
O8 - Extra context menu item: Subscribe to Feed - res://C:\Program Files\JetBrains\Omea Reader\IexploreOmeaW.dll/1002
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_03\bin\ssv.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_03\bin\ssv.dll
O9 - Extra button: ICQ Pro - {6224f700-cba3-4071-b251-47cb894244cd} - C:\PROGRA~1\ICQ\ICQ.exe
O9 - Extra 'Tools' menuitem: ICQ - {6224f700-cba3-4071-b251-47cb894244cd} - C:\PROGRA~1\ICQ\ICQ.exe
O9 - Extra button: Add to EverNote - {A5ABA0BB-F195-40d8-A5E9-0801153E6597} - C:\Program Files\EverNote\EverNote\enbar.dll
O9 - Extra 'Tools' menuitem: Add to EverNote - {A5ABA0BB-F195-40d8-A5E9-0801153E6597} - C:\Program Files\EverNote\EverNote\enbar.dll
O9 - Extra button: AIM - {AC9E2541-2814-11d5-BC6D-00B0D0A1DE45} - C:\Program Files\AIM\aim.exe
O9 - Extra button: Real.com - {CD67F990-D8E9-11d2-98FE-00C0F0318AFE} - C:\WINDOWS\System32\Shdocvw.dll
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - %windir%\Network Diagnostic\xpnetdiag.exe (file missing)
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - %windir%\Network Diagnostic\xpnetdiag.exe (file missing)
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra button: Spurl! - {057AB0AA-0896-44A7-9940-1D3118C870FB} - http://www.spurl.net/rclick.php (file missing) (HKCU)
O9 - Extra 'Tools' menuitem: Bookmark the current page to Spurl.net - {057AB0AA-0896-44A7-9940-1D3118C870FB} - http://www.spurl.net/rclick.php (file missing) (HKCU)
O9 - Extra button: Spurl bar - {104D0F17-ED01-4E81-8EFF-53E956FC6D49} - Shdocvw.dll (file missing) (HKCU)
O9 - Extra 'Tools' menuitem: Spurl bar - {104D0F17-ED01-4E81-8EFF-53E956FC6D49} - Shdocvw.dll (file missing) (HKCU)
O9 - Extra button: (no name) - {35402C01-1777-4159-9ABA-3480BA70D901} - C:\Program Files\JetBrains\Omea Reader\IexploreOmeaW.dll (HKCU)
O9 - Extra 'Tools' menuitem: Omea Add-on Options… - {35402C01-1777-4159-9ABA-3480BA70D901} - C:\Program Files\JetBrains\Omea Reader\IexploreOmeaW.dll (HKCU)
O9 - Extra button: Subscribe to Feed - {35402C01-1777-4159-9ABA-3480BA70D903} - C:\Program Files\JetBrains\Omea Reader\IexploreOmeaW.dll (HKCU)
O9 - Extra button: Clip and Edit - {35402C01-1777-4159-9ABA-3480BA70D905} - C:\Program Files\JetBrains\Omea Reader\IexploreOmeaW.dll (HKCU)
O9 - Extra button: Clip and Save - {35402C01-1777-4159-9ABA-3480BA70D907} - C:\Program Files\JetBrains\Omea Reader\IexploreOmeaW.dll (HKCU)
O9 - Extra button: Annotate - {35402C01-1777-4159-9ABA-3480BA70D909} - C:\Program Files\JetBrains\Omea Reader\IexploreOmeaW.dll (HKCU)
O9 - Extra button: NeoTrace It! - {9885224C-1217-4c5f-83C2-00002E6CEF2B} - C:\PROGRA~1\NEOTRA~1\NTXtoolbar.htm (HKCU)
O11 - Options group: [INTERNATIONAL] International*
O16 - DPF: {01010E00-5E80-11D8-9E86-0007E96C65AE} (SupportSoft SmartIssue) - http://www.symantec.com/techsupp/asa/ctrl/tgctlsi.cab
O16 - DPF: {01012101-5E80-11D8-9E86-0007E96C65AE} (SupportSoft Script Runner Class) - http://www.symantec.com/techsupp/asa/ctrl/tgctlsr.cab
O16 - DPF: {193C772A-87BE-4B19-A7BB-445B226FE9A1} (ewidoOnlineScan Control) - http://downloads.ewido.net/ewidoOnlineScan.cab
O16 - DPF: {1F2F4C9E-6F09-47BC-970D-3C54734667FE} - https://www-secure.symantec.com/techsupp/as…rl/LSSupCtl.cab
O16 - DPF: {30528230-99f7-4bb4-88d8-fa1d4f56a2ab} (YInstStarter Class) - C:\Program Files\Yahoo!\Common\yinsthelper.dll
O16 - DPF: {7F8C8173-AD80-4807-AA75-5672F22B4582} (ICSScanner Class) - http://download.zonelabs.com/bin/promotion…canner37540.cab
O16 - DPF: {CB50428B-657F-47DF-9B32-671F82AA73F7} (Photodex Presenter AX control) - http://www.photodex.com/pxplay.cab
O16 - DPF: {CE28D5D2-60CF-4C7D-9FE8-0F47A3308078} (ActiveDataInfo Class) - https://www-secure.symantec.com/techsupp/as…rl/SymAData.cab
O20 - AppInit_DLLs: C:\WINDOWS\system32\guard32.dll
O20 - Winlogon Notify: WgaLogon - C:\WINDOWS\SYSTEM32\WgaLogon.dll
O21 - SSODL: WPDShServiceObj - {AAA288BA-9A4C-45B0-95D7-94D524869DB5} - C:\WINDOWS\system32\WPDShServiceObj.dll
O23 - Service: Ad-Aware 2007 Service (aawservice) - Lavasoft - C:\Program Files\Lavasoft\Ad-Aware 2007\aawservice.exe
O23 - Service: avast! iAVS4 Control Service (aswUpdSv) - ALWIL Software - C:\Program Files\Avast4\aswUpdSv.exe
O23 - Service: avast! Antivirus - ALWIL Software - C:\Program Files\Avast4\ashServ.exe
O23 - Service: avast! Mail Scanner - Unknown owner - C:\Program Files\Avast4\ashMaiSv.exe" /service (file missing)
O23 - Service: avast! Web Scanner - Unknown owner - C:\Program Files\Avast4\ashWebSv.exe" /service (file missing)
O23 - Service: Canon Camera Access Library 8 (CCALib8) - Canon Inc. - C:\Program Files\Canon\CAL\CALMAIN.exe
O23 - Service: COMODO Firewall Pro Helper Service (cmdAgent) - COMODO - C:\Program Files\COMODO\Firewall\cmdagent.exe
O23 - Service: Creative Service for CDROM Access - Creative Technology Ltd - C:\WINDOWS\System32\CTsvcCDA.exe
O23 - Service: Diskeeper - Executive Software International, Inc. - C:\Program Files\Diskeeper\DkService.exe
O23 - Service: Google Updater Service (gusvc) - Google - C:\Program Files\Google\Common\Google Updater\GoogleUpdaterService.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\11\Intel 32\IDriverT.exe
O23 - Service: InCD Helper (read only) (InCDsrvR) - Ahead Software AG - C:\Program Files\Ahead\InCD\InCDsrv.exe
O23 - Service: Iomega App Services - Iomega Corporation - C:\PROGRA~1\Iomega\System32\AppServices.exe
O23 - Service: Intel NCS NetService (NetSvc) - Intel® Corporation - C:\Program Files\Intel\NCS\Sync\NetSvc.exe
O23 - Service: NVIDIA Display Driver Service (NVSvc) - NVIDIA Corporation - C:\WINDOWS\system32\nvsvc32.exe
O23 - Service: Retrospect Launcher (RetroLauncher) - Dantz Development Corporation - C:\Program Files\Dantz\Retrospect\retrorun.exe
O23 - Service: Retrospect Helper - Dantz Development Corporation - C:\Program Files\Dantz\Retrospect\rthlpsvc.exe
O23 - Service: Retrospect WD Service (RetroWDSvc) - Dantz Development Corporation - C:\PROGRA~1\Dantz\RETROS~1\wdsvc.exe
O23 - Service: ScsiAccess - Unknown owner - C:\Program Files\Photodex\ProShowGold\ScsiAccess.exe
O23 - Service: Symantec Core LC - Unknown owner - C:\Program Files\Common Files\Symantec Shared\CCPD-LC\symlcsvc.exe (file missing)
O23 - Service: Iomega Active Disk (_IOMEGA_ACTIVE_DISK_SERVICE_) - Iomega Corporation - C:\Program Files\Iomega\AutoDisk\ADService.exe