I've noticed some system-wide slowdowns and here the generic explorer clicking sound. I have all windows sounds turned off so that concerns me.

Here's the log:

Logfile of HijackThis v1.99.1
Scan saved at 4:36:58 PM, on 9/20/2007
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v7.00 (7.00.6000.16512)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Common Files\Symantec Shared\ccSvcHst.exe
C:\Program Files\Common Files\Symantec Shared\AppCore\AppSvc32.exe
C:\WINDOWS\System32\WLTRYSVC.EXE
C:\WINDOWS\System32\bcmwltry.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Common Files\LogiShrd\LVMVFM\LVPrcSrv.exe
C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
C:\Program Files\Symantec\LiveUpdate\ALUSchedulerSvc.exe
C:\Program Files\Grisoft\AVG Anti-Spyware 7.5\guard.exe
C:\Program Files\Bonjour\mDNSResponder.exe
C:\Program Files\FolderSize\FolderSizeSvc.exe
C:\WINDOWS\system32\inetsrv\inetinfo.exe
C:\Program Files\Common Files\LogiShrd\LVCOMSER\LVComSer.exe
C:\WINDOWS\system32\nvsvc32.exe
C:\Program Files\Prevx2\PXAgent.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\Explorer.EXE
C:\Program Files\Common Files\LogiShrd\LVCOMSER\LVComSer.exe
C:\WINDOWS\system32\WLTRAY.exe
C:\WINDOWS\system32\rundll32.exe
C:\Program Files\Apoint\Apoint.exe
C:\Program Files\Google\Gmail Notifier\gnotify.exe
C:\WINDOWS\stsystra.exe
C:\Program Files\Adobe\Adobe Photoshop Lightroom 1.1\apdproxy.exe
C:\Program Files\Common Files\LogiShrd\LComMgr\Communications_Helper.exe
C:\Program Files\Logitech\QuickCam\Quickcam.exe
C:\Program Files\Apoint\Apntex.exe
C:\Program Files\Apoint\HidFind.exe
C:\Program Files\Common Files\Symantec Shared\ccApp.exe
C:\Program Files\iTunes\iTunesHelper.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Skype\Phone\Skype.exe
C:\Program Files\Microsoft Xbox 360 Accessories\XboxStat.exe
C:\Program Files\Prevx2\PXConsole.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\Common Files\Logishrd\LQCVFX\COCIManager.exe
C:\Program Files\Skype\Plugin Manager\skypePM.exe
C:\Program Files\iPod\bin\iPodService.exe
C:\Program Files\Mozilla Firefox\firefox.exe
C:\Program Files\Hijackthis\HijackThis.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = https://system2.ipressroom.com/main.asp
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
F2 - REG:system.ini: UserInit=userinit.exe
O2 - BHO: Adobe PDF Reader Link Helper - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 7.0\ActiveX\AcroIEHelper.dll
O2 - BHO: Malicious Scripts Scanner - {55EA1964-F5E4-4D6A-B9B2-125B37655FCB} - C:\Documents and Settings\All Users\Application Data\Prevx\pxbho.dll
O2 - BHO: NCO 2.0 IE BHO - {602ADB0E-4AFF-4217-8AA1-95DAC4DFA408} - (no file)
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.6.0_01\bin\ssv.dll
O3 - Toolbar: (no name) - {7FEBEFE3-6B19-4349-98D2-FFB09D4B49CA} - (no file)
O4 - HKLM\..\Run: [Broadcom Wireless Manager UI] C:\WINDOWS\system32\WLTRAY.exe
O4 - HKLM\..\Run: [NVHotkey] rundll32.exe nvHotkey.dll,Start
O4 - HKLM\..\Run: [Apoint] C:\Program Files\Apoint\Apoint.exe
O4 - HKLM\..\Run: [{0228e555-4f9c-4e35-a3ec-b109a192b4c2}] C:\Program Files\Google\Gmail Notifier\gnotify.exe
O4 - HKLM\..\Run: [SigmatelSysTrayApp] stsystra.exe
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE C:\WINDOWS\system32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [nwiz] nwiz.exe /installquiet
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\QTTask.exe" -atboottime
O4 - HKLM\..\Run: [Adobe Photo Downloader] "C:\Program Files\Adobe\Adobe Photoshop Lightroom 1.1\apdproxy.exe"
O4 - HKLM\..\Run: [LogitechCommunicationsManager] "C:\Program Files\Common Files\LogiShrd\LComMgr\Communications_Helper.exe"
O4 - HKLM\..\Run: [LogitechQuickCamRibbon] "C:\Program Files\Logitech\QuickCam\Quickcam.exe" /hide
O4 - HKLM\..\Run: [ccApp] "C:\Program Files\Common Files\Symantec Shared\ccApp.exe"
O4 - HKLM\..\Run: [osCheck] "C:\Program Files\Norton AntiVirus\osCheck.exe"
O4 - HKLM\..\Run: [Symantec PIF AlertEng] "C:\Program Files\Common Files\Symantec Shared\PIF\{B8E1DD85-8582-4c61-B58F-2F227FCA9A08}\PIFSvc.exe" /a /m "C:\Program Files\Common Files\Symantec Shared\PIF\{B8E1DD85-8582-4c61-B58F-2F227FCA9A08}\AlertEng.dll"
O4 - HKLM\..\Run: [iTunesHelper] "C:\Program Files\iTunes\iTunesHelper.exe"
O4 - HKLM\..\Run: [XboxStat] "c:\Program Files\Microsoft Xbox 360 Accessories\XboxStat.exe" silentrun
O4 - HKLM\..\Run: [PrevxOne] "C:\Program Files\Prevx2\PXConsole.exe"
O4 - HKLM\..\RunOnce: [WIAWizardMenu] RUNDLL32.EXE C:\WINDOWS\system32\sti_ci.dll,WiaCreateWizardMenu
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~3\OFFICE11\EXCEL.EXE/3000
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~3\OFFICE11\REFIEBAR.DLL
O10 - Unknown file in Winsock LSP: c:\program files\bonjour\mdnsnsp.dll
O11 - Options group: [INTERNATIONAL] International*
O16 - DPF: {01A88BB1-1174-41EC-ACCB-963509EAE56B} (SysProWmi Class) - http://support.dell.com/systemprofiler/SysPro.CAB
O16 - DPF: {6E32070A-766D-4EE6-879C-DC1FA91D2FC3} (MUWebControl Class) - http://www.update.microsoft.com/microsoftu…b?1181771182687
O16 - DPF: {D27CDB6E-AE6D-11CF-96B8-444553540000} (Shockwave Flash Object) - http://fpdownload2.macromedia.com/get/shoc…ash/swflash.cab
O16 - DPF: {E87F6C8E-16C0-11D3-BEF7-009027438003} (Persits Software XUpload) - https://system2.ipressroom.com/system/xuplo…101/XUpload.ocx
O18 - Protocol: ms-help - {314111C7-A502-11D2-BBCA-00C04F8EC294} - C:\Program Files\Common Files\Microsoft Shared\Help\hxds.dll
O18 - Protocol: skype4com - {FFC8B962-9B40-4DFF-9458-1830C7DD7F5D} - C:\PROGRA~1\COMMON~1\Skype\SKYPE4~1.DLL
O20 - Winlogon Notify: WgaLogon - C:\WINDOWS\SYSTEM32\WgaLogon.dll
O21 - SSODL: WPDShServiceObj - {AAA288BA-9A4C-45B0-95D7-94D524869DB5} - C:\WINDOWS\system32\WPDShServiceObj.dll
O23 - Service: Adobe LM Service - Adobe Systems - C:\Program Files\Common Files\Adobe Systems Shared\Service\Adobelmsvc.exe
O23 - Service: Apple Mobile Device - Apple, Inc. - C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
O23 - Service: Automatic LiveUpdate Scheduler - Symantec Corporation - C:\Program Files\Symantec\LiveUpdate\ALUSchedulerSvc.exe
O23 - Service: AVG Anti-Spyware Guard - GRISOFT s.r.o. - C:\Program Files\Grisoft\AVG Anti-Spyware 7.5\guard.exe
O23 - Service: ##Id_String1.6844F930_1628_4223_B5CC_5BB94B879762## (Bonjour Service) - Apple Computer, Inc. - C:\Program Files\Bonjour\mDNSResponder.exe
O23 - Service: Symantec Event Manager (ccEvtMgr) - Unknown owner - C:\Program Files\Common Files\Symantec Shared\ccSvcHst.exe" /h ccCommon (file missing)
O23 - Service: Symantec Settings Manager (ccSetMgr) - Unknown owner - C:\Program Files\Common Files\Symantec Shared\ccSvcHst.exe" /h ccCommon (file missing)
O23 - Service: Symantec Lic NetConnect service (CLTNetCnService) - Unknown owner - C:\Program Files\Common Files\Symantec Shared\ccSvcHst.exe" /h ccCommon (file missing)
O23 - Service: Folder Size (FolderSize) - Brio - C:\Program Files\FolderSize\FolderSizeSvc.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\11\Intel 32\IDriverT.exe
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: Symantec IS Password Validation (ISPwdSvc) - Symantec Corporation - C:\Program Files\Norton AntiVirus\isPwdSvc.exe
O23 - Service: LiveUpdate - Symantec Corporation - C:\PROGRA~1\Symantec\LIVEUP~1\LUCOMS~1.EXE
O23 - Service: LiveUpdate Notice Service Ex (LiveUpdate Notice Ex) - Unknown owner - C:\Program Files\Common Files\Symantec Shared\ccSvcHst.exe" /h ccCommon (file missing)
O23 - Service: LiveUpdate Notice Service - Unknown owner - C:\Program Files\Common Files\Symantec Shared\PIF\{B8E1DD85-8582-4c61-B58F-2F227FCA9A08}\PIFSvc.exe" /m "C:\Program Files\Common Files\Symantec Shared\PIF\{B8E1DD85-8582-4c61-B58F-2F227FCA9A08}\PifEng.dll (file missing)
O23 - Service: LVCOMSer - Logitech Inc. - C:\Program Files\Common Files\LogiShrd\LVCOMSER\LVComSer.exe
O23 - Service: Process Monitor (LVPrcSrv) - Logitech Inc. - C:\Program Files\Common Files\LogiShrd\LVMVFM\LVPrcSrv.exe
O23 - Service: LVSrvLauncher - Logitech Inc. - C:\Program Files\Common Files\LogiShrd\SrvLnch\SrvLnch.exe
O23 - Service: SQL Server (SQLEXPRESS) (MSSQL$SQLEXPRESS) - Unknown owner - c:\Program Files\Microsoft SQL Server\MSSQL.1\MSSQL\Binn\sqlservr.exe" -sSQLEXPRESS (file missing)
O23 - Service: NVIDIA Display Driver Service (NVSvc) - NVIDIA Corporation - C:\WINDOWS\system32\nvsvc32.exe
O23 - Service: PREVXAgent - Unknown owner - C:\Program Files\Prevx2\PXAgent.exe" -f (file missing)
O23 - Service: Symantec Core LC - Symantec Corporation - C:\Program Files\Common Files\Symantec Shared\CCPD-LC\symlcsvc.exe
O23 - Service: Symantec AppCore Service (SymAppCore) - Symantec Corporation - C:\Program Files\Common Files\Symantec Shared\AppCore\AppSvc32.exe
O23 - Service: Dell Wireless WLAN Tray Service (wltrysvc) - Unknown owner - C:\WINDOWS\System32\WLTRYSVC.EXE

I don't know if this is related but: Another thing I've noticed recently is that Explorer.exe freaks out and my taskbar freezes whenever I attach a USB storage device.

Any help would be greatly appreciated.

Thanks!