Unsen Pop Ups

I have realized that my computer is opening html pages from my Documents and Settings > Local Settings > Temp and they are taking me to places like MicroSoft-Corp1, MicroSoft-Corp10 and things like that, I have run every kind of software to remove malicious carp**, but it doesnt seem to be working. I never see these pages, they do not open up in a browser, but when I go to the directory and click on them I see what they are. I have tried to delete them and they just come back. I can see them open when I have my task manager open

Ok, first, download Hijack This here and then scan but do not fix anything yet. Save your scan to a log file then click here to post your log into a new thread in the "hijack this logs and spyware/malware removal" forum.