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I got a major problem

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On my add/remove programs list there was no new.net or newdot.net. There was this one program called "The Best Offers" but in order to uninstall it, it says I need to download an uninstaller from its website. Should i download it?
Logfile of HijackThis v1.99.1
Scan saved at 8:15:07 PM, on 09/13/2005
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\System32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Common Files\EPSON\EBAPI\SAgent2.exe
C:\Program Files\ewido\security suite\ewidoctrl.exe
C:\WINDOWS\System32\nvsvc32.exe
C:\PROGRA~1\TRENDM~1\INTERN~1\PcCtlCom.exe
C:\PROGRA~1\TRENDM~1\INTERN~1\Tmntsrv.exe
C:\PROGRA~1\TRENDM~1\INTERN~1\tmproxy.exe
C:\Program Files\Citrix\ICA Client\ssonsvr.exe
C:\WINDOWS\wanmpsvc.exe
C:\WINDOWS\system32\userinit.exe
C:\WINDOWS\Explorer.EXE
C:\program files\support.com\client\bin\tgcmd.exe
C:\WINDOWS\System32\ezSP_Px.exe
C:\Program Files\QuickTime\qttask.exe
C:\Program Files\Common Files\Real\Update_OB\realsched.exe
C:\Program Files\Trend Micro\Internet Security 2005\pccguide.exe
C:\Program Files\Java\jre1.5.0_03\bin\jusched.exe
C:\Program Files\Sony\VAIO Action Setup\VAServ.exe
C:\Documents and Settings\Tonia\Favorites\Messenger\ymsgr_tray.exe
C:\WINDOWS\System32\spool\DRIVERS\W32X86\3\E_S10IC2.EXE
C:\PROGRA~1\TRENDM~1\INTERN~1\TmPfw.exe
D:\Program Files\Hijack This\HijackThis[1].exe

R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://home.excite.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://us.rd.yahoo.com/customize/ie/defaul…//www.yahoo.com
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://us.rd.yahoo.com/customize/ie/defaul…//www.yahoo.com
R1 - HKCU\Software\Microsoft\Internet Explorer\SearchURL,(Default) = http://us.rd.yahoo.com/customize/ie/defaul…//www.yahoo.com
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyServer = proxy:8080
O2 - BHO: Google Toolbar Helper - {AA58ED58-01DD-4d91-8333-CF10577473F7} - c:\program files\google\googletoolbar2.dll
O2 - BHO: OsbornTech Popup Blocker - {C68AE9C0-0909-4DDC-B661-C1AFB9F5AE53} - C:\Program Files\DefenderPro AntiSpy\PopupBlocker\PopupBlocker.dll
O3 - Toolbar: &Google - {2318C2B1-4965-11d4-9B18-009027A5CD4F} - c:\program files\google\googletoolbar2.dll
O4 - HKLM\..\Run: [ZTgServerSwitch] c:\program files\support.com\client\bin\tgcmd.exe /server
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE NvQTwk,NvCplDaemon initialize
O4 - HKLM\..\Run: [ezShieldProtector for Px] C:\WINDOWS\System32\ezSP_Px.exe
O4 - HKLM\..\Run: [Pure Networks Port Magic] "C:\PROGRA~1\PURENE~1\PORTMA~1\PortAOL.exe" -Run
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [TkBellExe] "C:\Program Files\Common Files\Real\Update_OB\realsched.exe" -osboot
O4 - HKLM\..\Run: [pccguide.exe] "C:\Program Files\Trend Micro\Internet Security 2005\pccguide.exe"
O4 - HKLM\..\Run: [SunJavaUpdateSched] C:\Program Files\Java\jre1.5.0_03\bin\jusched.exe
O4 - HKCU\..\Run: [Yahoo! Pager] "C:\Documents and Settings\Tonia\Favorites\Messenger\ypager.exe" -quiet
O4 - HKCU\..\Run: [msnmsgr] "C:\Program Files\MSN Messenger\msnmsgr.exe" /background
O4 - HKCU\..\Run: [SpyKiller] C:\Program Files\SpyKiller\spykiller.exe /startup
O4 - HKCU\..\Run: [BestPopUpKiller] C:\Program Files\BestPopUpKiller\BestPopupKiller.exe /startup
O4 - Global Startup: America Online Tray Icon.lnk = C:\Program Files\America Online 8.0\aoltray.exe
O4 - Global Startup: EPSON Status Monitor 3 Environment Check 2.lnk = C:\WINDOWS\system32\spool\drivers\w32x86\3\E_SRCV02.EXE
O4 - Global Startup: Microsoft Office.lnk = C:\Program Files\Microsoft Office\Office\OSA9.EXE
O4 - Global Startup: VAIO Action Setup (Server).lnk = ?
O8 - Extra context menu item: &AOL Toolbar search - res://C:\Program Files\AOL Toolbar\toolbar.dll/SEARCH.HTML
O8 - Extra context menu item: &Google Search - res://c:\program files\google\GoogleToolbar2.dll/cmsearch.html
O8 - Extra context menu item: &Yahoo! Search - file:///C:\Documents and Settings\Tonia\Favorites\Common/ycsrch.htm
O8 - Extra context menu item: Backward Links - res://c:\program files\google\GoogleToolbar2.dll/cmbacklinks.html
O8 - Extra context menu item: Cached Snapshot of Page - res://c:\program files\google\GoogleToolbar2.dll/cmcache.html
O8 - Extra context menu item: Similar Pages - res://c:\program files\google\GoogleToolbar2.dll/cmsimilar.html
O8 - Extra context menu item: Translate into English - res://c:\program files\google\GoogleToolbar2.dll/cmtrans.html
O8 - Extra context menu item: Yahoo! &Dictionary - file:///C:\Documents and Settings\Tonia\Favorites\Common/ycdict.htm
O8 - Extra context menu item: Yahoo! &Maps - file:///C:\Documents and Settings\Tonia\Favorites\Common/ycmap.htm
O8 - Extra context menu item: Yahoo! &SMS - file:///C:\Documents and Settings\Tonia\Favorites\Common/ycsms.htm
O9 - Extra button: Popup Blocker - {0D555BC6-E331-48b3-A60E-AAC0DF79438A} - C:\Program Files\DefenderPro AntiSpy\PopupBlocker\PopupBlocker.dll
O9 - Extra 'Tools' menuitem: Popup Blocker - {0D555BC6-E331-48b3-A60E-AAC0DF79438A} - C:\Program Files\DefenderPro AntiSpy\PopupBlocker\PopupBlocker.dll
O9 - Extra button: Yahoo! Services - {5BAB4B5B-68BC-4B02-94D6-2FC0DE4A7897} - C:\Documents and Settings\Tonia\Favorites\Common\yiesrvc.dll
O9 - Extra button: (no name) - {CD67F990-D8E9-11d2-98FE-00C0F0318AFE} - (no file)
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra button: @Home - {2BF1D1A7-5E21-4B1B-9FF2-B895EF933D15} - http://home.excite.com (file missing) (HKCU)
O12 - Plugin for .spop: C:\Program Files\Internet Explorer\Plugins\NPDocBox.dll
O14 - IERESET.INF: START_PAGE_URL=http://home.excite.com/
O23 - Service: EPSON Printer Status Agent2 (EPSONStatusAgent2) - SEIKO EPSON CORPORATION - C:\Program Files\Common Files\EPSON\EBAPI\SAgent2.exe
O23 - Service: ewido security suite control - ewido networks - C:\Program Files\ewido\security suite\ewidoctrl.exe
O23 - Service: NVIDIA Driver Helper Service (NVSvc) - NVIDIA Corporation - C:\WINDOWS\System32\nvsvc32.exe
O23 - Service: Trend Micro Central Control Component (PcCtlCom) - Trend Micro Incorporated. - C:\PROGRA~1\TRENDM~1\INTERN~1\PcCtlCom.exe
O23 - Service: Sony SPTI Service (SPTISRV) - Sony Corporation - C:\PROGRA~1\COMMON~1\SONYSH~1\AVLib\Sptisrv.exe
O23 - Service: Trend Micro Real-time Service (Tmntsrv) - Trend Micro Incorporated. - C:\PROGRA~1\TRENDM~1\INTERN~1\Tmntsrv.exe
O23 - Service: Trend Micro Personal Firewall (TmPfw) - Trend Micro Inc. - C:\PROGRA~1\TRENDM~1\INTERN~1\TmPfw.exe
O23 - Service: Trend Micro Proxy Service (tmproxy) - Trend Micro Inc. - C:\PROGRA~1\TRENDM~1\INTERN~1\tmproxy.exe
O23 - Service: WAN Miniport (ATW) Service (WANMiniportService) - America Online, Inc. - C:\WINDOWS\wanmpsvc.exe
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