Computer has been very slow lately. Cna someone please evaluate my hijack this log?

Logfile of HijackThis v1.99.1
Scan saved at 3:26:45 PM, on 4/26/2008
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v7.00 (7.00.6000.16640)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\System32\Ati2evxx.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
C:\Program Files\Bonjour\mDNSResponder.exe
C:\WINDOWS\system32\cisvc.exe
C:\WINDOWS\ehome\ehSched.exe
C:\PROGRA~1\McAfee\MSC\mcmscsvc.exe
c:\program files\common files\mcafee\mna\mcnasvc.exe
c:\PROGRA~1\COMMON~1\mcafee\mcproxy\mcproxy.exe
C:\PROGRA~1\McAfee\VIRUSS~1\mcshield.exe
C:\Program Files\McAfee\MPF\MPFSrv.exe
C:\Program Files\SiteAdvisor\6253\SAService.exe
C:\Program Files\Analog Devices\SoundMAX\spkrmon.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\Explorer.EXE
C:\PROGRA~1\McAfee.com\Agent\mcagent.exe
C:\WINDOWS\ehome\ehtray.exe
C:\Program Files\Real\RealPlayer\RealPlay.exe
C:\Program Files\Common Files\Dell\EUSW\Support.exe
C:\WINDOWS\system32\dla\tfswctrl.exe
C:\WINDOWS\ehome\ehmsas.exe
C:\Program Files\iTunes\iTunesHelper.exe
C:\Program Files\Messenger\msmsgs.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\Dell\Support\Alert\bin\NotifyAlert.exe
C:\Program Files\iPod\bin\iPodService.exe
C:\WINDOWS\System32\svchost.exe
C:\PROGRA~1\McAfee\VIRUSS~1\mcsysmon.exe
C:\Program Files\SiteAdvisor\6253\SiteAdv.exe
C:\WINDOWS\system32\cidaemon.exe
C:\WINDOWS\system32\cidaemon.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\WINDOWS\system32\wuauclt.exe
C:\Program Files\Hijackthis\HijackThis.exe

R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
O2 - BHO: Adobe PDF Reader Link Helper - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 7.0\ActiveX\AcroIEHelper.dll
O2 - BHO: (no name) - {089FD14D-132B-48FC-8861-0048AE113215} - C:\Program Files\SiteAdvisor\6253\SiteAdv.dll
O2 - BHO: Spybot-S&D IE Protection - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O2 - BHO: DriveLetterAccess - {5CA3D70E-1895-11CF-8E15-001234567890} - C:\WINDOWS\system32\dla\tfswshx.dll
O2 - BHO: scriptproxy - {7DB2D5A0-7241-4E79-B68D-6309F01C5231} - C:\Program Files\McAfee\VirusScan\scriptsn.dll
O3 - Toolbar: McAfee SiteAdvisor - {0BF43445-2F28-4351-9252-17FE6E806AA0} - C:\Program Files\SiteAdvisor\6253\SiteAdv.dll
O4 - HKLM\..\Run: [ehTray] C:\WINDOWS\ehome\ehtray.exe
O4 - HKLM\..\Run: [ATIModeChange] Ati2mdxx.exe
O4 - HKLM\..\Run: [ATIPTA] C:\Program Files\ATI Technologies\ATI Control Panel\atiptaxx.exe
O4 - HKLM\..\Run: [RealTray] C:\Program Files\Real\RealPlayer\RealPlay.exe SYSTEMBOOTHIDEPLAYER
O4 - HKLM\..\Run: [DwlClient] C:\Program Files\Common Files\Dell\EUSW\Support.exe
O4 - HKLM\..\Run: [dla] C:\WINDOWS\system32\dla\tfswctrl.exe
O4 - HKLM\..\Run: [StorageGuard] "C:\Program Files\Common Files\Sonic\Update Manager\sgtray.exe" /r
O4 - HKLM\..\Run: [mcagent_exe] C:\Program Files\McAfee.com\Agent\mcagent.exe /runkey
O4 - HKLM\..\Run: [PinnacleDriverCheck] C:\WINDOWS\system32\\PSDrvCheck.exe
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [iTunesHelper] "C:\Program Files\iTunes\iTunesHelper.exe"
O4 - HKCU\..\Run: [MSMSGS] "C:\Program Files\Messenger\msmsgs.exe" /background
O4 - HKCU\..\Run: [updateMgr] "C:\Program Files\Adobe\Acrobat 7.0\Reader\AdobeUpdateManager.exe" AcRdB7_0_9 -reboot 1
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - Startup: PowerReg Scheduler V3.exe
O4 - Global Startup: Adobe Reader Speed Launch.lnk = C:\Program Files\Adobe\Acrobat 7.0\Reader\reader_sl.exe
O4 - Global Startup: Microsoft Office.lnk = C:\Program Files\Microsoft Office\Office10\OSA.EXE
O9 - Extra button: Real.com - {CD67F990-D8E9-11d2-98FE-00C0F0318AFE} - C:\WINDOWS\System32\Shdocvw.dll
O9 - Extra button: (no name) - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra 'Tools' menuitem: Spybot - Search & Destroy Configuration - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - %windir%\Network Diagnostic\xpnetdiag.exe (file missing)
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - %windir%\Network Diagnostic\xpnetdiag.exe (file missing)
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O10 - Unknown file in Winsock LSP: c:\program files\bonjour\mdnsnsp.dll
O11 - Options group: [INTERNATIONAL] International*
O16 - DPF: {4ED9DDF0-7479-4BBE-9335-5A1EDB1D8A21} (McAfee.com Operating System Class) - http://download.mcafee.com/molbin/shared/m…01/mcinsctl.cab
O16 - DPF: {BCC0FF27-31D9-4614-A68E-C18E1ADA4389} (DwnldGroupMgr Class) - http://download.mcafee.com/molbin/shared/m…,26/mcgdmgr.cab
O18 - Protocol: siteadvisor - {3A5DC592-7723-4EAA-9EE6-AF4222BCF879} - C:\Program Files\SiteAdvisor\6253\SiteAdv.dll
O20 - Winlogon Notify: WgaLogon - C:\WINDOWS\SYSTEM32\WgaLogon.dll
O23 - Service: McAfee Application Installer Cleanup (0079271203172442) (0079271203172442mcinstcleanup) - Unknown owner - C:\WINDOWS\TEMP\007927~1.EXE (file missing)
O23 - Service: Apple Mobile Device - Apple, Inc. - C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
O23 - Service: Ati HotKey Poller - Unknown owner - C:\WINDOWS\System32\Ati2evxx.exe
O23 - Service: Bonjour Service - Apple Inc. - C:\Program Files\Bonjour\mDNSResponder.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\11\Intel 32\IDriverT.exe
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: McAfee Services (mcmscsvc) - McAfee, Inc. - C:\PROGRA~1\McAfee\MSC\mcmscsvc.exe
O23 - Service: McAfee Network Agent (McNASvc) - McAfee, Inc. - c:\program files\common files\mcafee\mna\mcnasvc.exe
O23 - Service: McAfee Scanner (McODS) - McAfee, Inc. - C:\PROGRA~1\McAfee\VIRUSS~1\mcods.exe
O23 - Service: McAfee Proxy Service (McProxy) - McAfee, Inc. - c:\PROGRA~1\COMMON~1\mcafee\mcproxy\mcproxy.exe
O23 - Service: McAfee Real-time Scanner (McShield) - McAfee, Inc. - C:\PROGRA~1\McAfee\VIRUSS~1\mcshield.exe
O23 - Service: McAfee SystemGuards (McSysmon) - McAfee, Inc. - C:\PROGRA~1\McAfee\VIRUSS~1\mcsysmon.exe
O23 - Service: McAfee Personal Firewall Service (MpfService) - McAfee, Inc. - C:\Program Files\McAfee\MPF\MPFSrv.exe
O23 - Service: SiteAdvisor Service - Unknown owner - C:\Program Files\SiteAdvisor\6253\SAService.exe
O23 - Service: spkrmon - Unknown owner - C:\Program Files\Analog Devices\SoundMAX\spkrmon.exe