I can't give you specific guidance, but with a couple of pointers I'm hoping it will give you what you need to sort this.
To start with you need to protect the link that gets these responses, there are bot's that do nothing but scour the net picking up such details, then adding them to spam lists, so I'm afraid that address used in your link is only going to get worse as spam lists get sold on, my best advice is once you have protected the link\address used, scrap that address and make a new one.
Now the link\address used, if you have it written as text, you need to find a way to make it so it can't be copied by a bot (which is where I start to drown lol), my approach on sites I have done was to make it an image, so all the bot see's is a .jpg or similar, the downside of this (which was pointed out to me) means those who are visually impaired who rely on a screen reader would not be able to respond to you if they needed, unfortunately at this stage I have drowned lol.
The only other option is to use filters, set some wild cards, e.g. *.domain.com (for those specific sites you want to block), also specific keywords, like Rolex, Viagra and the like, initially it will be a lot of work, and it won't stop them from happening, but it does stop them getting to your inbox, but over time your list will become so big it may cause issues itself (I don't know enough in this area), as I have to wonder if there is any kind of limit to the amount of these you can do.
Sorry I don't know enough to give you anything more specific, but I hope this inspires you as to what to do, hope it helps and good luck.