Help, please!

I will appreciate it if anyone can help with this one:

Logfile of HijackThis v1.99.1
Scan saved at 9:12:30 AM, on 8/21/2006
Platform: Windows 2000 SP4 (WinNT 5.00.2195)
MSIE: Internet Explorer v6.00 SP1 (6.00.2800.1106)

Running processes:
C:\WINNT\System32\smss.exe
C:\WINNT\system32\winlogon.exe
C:\WINNT\system32\services.exe
C:\WINNT\system32\lsass.exe
C:\WINNT\system32\svchost.exe
C:\WINNT\system32\spoolsv.exe
C:\PROGRA~1\SYMANT~1\SYMANT~1\DefWatch.exe
C:\WINNT\System32\svchost.exe
C:\PROGRA~1\SYMANT~1\SYMANT~1\Rtvscan.exe
C:\WINNT\system32\regsvc.exe
C:\WINNT\system32\MSTask.exe
C:\Program Files\Webroot\Enterprise\CommAgent\CommAgent.exe
C:\WINNT\System32\WBEM\WinMgmt.exe
C:\WINNT\system32\mspmspsv.exe
C:\WINNT\system32\svchost.exe
C:\WINNT\Explorer.EXE
C:\Program Files\IntCodec\isamonitor.exe
C:\Program Files\IntCodec\pmsngr.exe
C:\WINNT\system32\Promon.exe
C:\Program Files\IntCodec\pmmon.exe
C:\Program Files\IntCodec\isamini.exe
C:\Program Files\Analog Devices\SoundMAX\Smtray.exe
C:\Program Files\Analog Devices\SoundMAX\DrvLsnr.exe
C:\PROGRA~1\SYMANT~1\SYMANT~1\vptray.exe
C:\WINNT\system32\spool\drivers\w32x86\3\hpztsb03.exe
C:\Program Files\Webroot\Enterprise\Spy Sweeper\SpySweeperTray.exe
C:\Program Files\iTunes\iTunesHelper.exe
C:\Program Files\QuickTime\qttask.exe
C:\WINNT\system32\internat.exe
C:\Program Files\Adobe\Acrobat 5.0\Distillr\AcroTray.exe
C:\Program Files\iPod\bin\iPodService.exe
C:\WINNT\system32\wuauclt.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\PROGRA~1\WinZip\winzip32.exe
C:\DOCUME~1\keelerb\LOCALS~1\Temp\HijackThis.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.cnn.com/
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyServer = http=ZillaPopupKiller:8100
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = local
R3 - URLSearchHook: (no name) - - (no file)
O2 - BHO: (no name) - {202a961f-23ae-42b1-9505-ffe3c818d717} - C:\Program Files\IntCodec\isaddon.dll
O2 - BHO: Google Toolbar Helper - {AA58ED58-01DD-4d91-8333-CF10577473F7} - c:\program files\google\googletoolbar2.dll
O3 - Toolbar: &Radio - {8E718888-423F-11D2-876E-00A0C9082467} - C:\WINNT\system32\MSDXM.OCX
O3 - Toolbar: &Google - {2318C2B1-4965-11d4-9B18-009027A5CD4F} - c:\program files\google\googletoolbar2.dll
O4 - HKLM\..\Run: [Synchronization Manager] mobsync.exe /logon
O4 - HKLM\..\Run: [Promon.exe] Promon.exe
O4 - HKLM\..\Run: [Smapp] C:\Program Files\Analog Devices\SoundMAX\Smtray.exe
O4 - HKLM\..\Run: [DrvLsnr] C:\Program Files\Analog Devices\SoundMAX\DrvLsnr.exe
O4 - HKLM\..\Run: [vptray] C:\PROGRA~1\SYMANT~1\SYMANT~1\vptray.exe
O4 - HKLM\..\Run: [HPDJ Taskbar Utility] C:\WINNT\system32\spool\drivers\w32x86\3\hpztsb03.exe
O4 - HKLM\..\Run: [Webroot Spy Sweeper, Enterprise Edition] C:\Program Files\Webroot\Enterprise\Spy Sweeper\SpySweeperTray.exe
O4 - HKLM\..\Run: [NeroFilterCheck] C:\WINNT\system32\NeroCheck.exe
O4 - HKLM\..\Run: [iTunesHelper] "C:\Program Files\iTunes\iTunesHelper.exe"
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKCU\..\Run: [internat.exe] internat.exe
O4 - HKCU\..\Run: [Yahoo! Pager] C:\Program Files\Yahoo!\Messenger\ypager.exe -quiet
O4 - Global Startup: Acrobat Assistant.lnk = C:\Program Files\Adobe\Acrobat 5.0\Distillr\AcroTray.exe
O4 - Global Startup: Microsoft Office.lnk = C:\Program Files\Office2k\Office\OSA9.EXE
O8 - Extra context menu item: &Google Search - res://c:\program files\google\GoogleToolbar2.dll/cmsearch.html
O8 - Extra context menu item: &Translate English Word - res://c:\program files\google\GoogleToolbar2.dll/cmwordtrans.html
O8 - Extra context menu item: Backward Links - res://c:\program files\google\GoogleToolbar2.dll/cmbacklinks.html
O8 - Extra context menu item: Cached Snapshot of Page - res://c:\program files\google\GoogleToolbar2.dll/cmcache.html
O8 - Extra context menu item: Similar Pages - res://c:\program files\google\GoogleToolbar2.dll/cmsimilar.html
O8 - Extra context menu item: Translate Page into English - res://c:\program files\google\GoogleToolbar2.dll/cmtrans.html
O9 - Extra button: AIM - {AC9E2541-2814-11d5-BC6D-00B0D0A1DE45} - C:\Program Files\AIM\aim.exe
O9 - Extra button: (no name) - {D5770C25-E0F4-4bb9-BCB6-DB17F7BFBB7F} - C:\Program Files\SafeGuard Popup Blocker Pro\PBOptions.exe (file missing)
O9 - Extra 'Tools' menuitem: Popup Blocker Options - {D5770C25-E0F4-4bb9-BCB6-DB17F7BFBB7F} - C:\Program Files\SafeGuard Popup Blocker Pro\PBOptions.exe (file missing)
O9 - Extra button: WeatherBug - {AF6CABAB-61F9-4f12-A198-B7D41EF1CB52} - C:\PROGRA~1\AWS\WEATHE~1\Weather.exe (HKCU)
O12 - Plugin for .spop: C:\Program Files\Internet Explorer\Plugins\NPDocBox.dll
O16 - DPF: {9A9307A0-7DA4-4DAF-B042-5009F29E09E1} (ActiveScan Installer Class) - http://www.pandasoftware.com/activescan/as5free/asinst.cab
O16 - DPF: {A0EAC162-A012-4AD8-B2E1-D5A0BBBCDA51} (PopupSh Control) - http://206.222.26.90/images/PopupSh.ocx
O16 - DPF: {C02226EB-A5D7-4B1F-BD7E-635E46C2288D} (Toontown Installer ActiveX Control) - http://a.download.toontown.com/sv1.0.20.19/ttinst.cab
O20 - Winlogon Notify: WRNotifier - WRLogonNTF.dll (file missing)
O21 - SSODL: bestreak - {874443fe-aa33-4ebf-a6ac-73208787e62d} - C:\WINNT\system32\viruxz.dll (file missing)
O23 - Service: DefWatch - Symantec Corporation - C:\PROGRA~1\SYMANT~1\SYMANT~1\DefWatch.exe
O23 - Service: Logical Disk Manager Administrative Service (dmadmin) - VERITAS Software Corp. - C:\WINNT\System32\dmadmin.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\11\Intel 32\IDriverT.exe
O23 - Service: iPodService - Apple Computer, Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: Symantec AntiVirus Client (Norton AntiVirus Server) - Symantec Corporation - C:\PROGRA~1\SYMANT~1\SYMANT~1\Rtvscan.exe
O23 - Service: Webroot CommAgent Service (WebrootCommAgentService) - Webroot Software, Inc. - C:\Program Files\Webroot\Enterprise\CommAgent\CommAgent.exe