When opening ie, there will be a random popup, please help me remove it.

Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 10:43:49 AM, on 8/8/2008
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v7.00 (7.00.6000.16674)
Boot mode: Normal

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\savedump.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\Ati2evxx.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\system32\Ati2evxx.exe
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\Explorer.EXE
C:\Program Files\VIA\VIAudioi\HDADeck\HDeck.exe
C:\Program Files\iTunes\iTunesHelper.exe
C:\Program Files\Windows Live\Messenger\MsnMsgr.Exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\ATI Technologies\ATI.ACE\CLI.EXE
C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
C:\Program Files\Bonjour\mDNSResponder.exe
C:\WINDOWS\system32\CTsvcCDA.EXE
C:\WINDOWS\System32\svchost.exe
C:\Program Files\iPod\bin\iPodService.exe
C:\Program Files\ATI Technologies\ATI.ACE\cli.exe
C:\Program Files\ATI Technologies\ATI.ACE\cli.exe
C:\Program Files\Windows Live\Messenger\usnsvc.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\wuauclt.exe
C:\Program Files\Trend Micro\HijackThis\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.neopets.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 5.0\Reader\ActiveX\AcroIEHelper.ocx
O2 - BHO: Megaupload Toolbar - {4E7BD74F-2B8D-469E-CCB0-B130EEDBE97C} - C:\PROGRA~1\MEGAUP~1\MEGAUP~1.DLL
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.6.0_05\bin\ssv.dll
O2 - BHO: (no name) - {7E853D72-626A-48EC-A868-BA8D5E23E045} - (no file)
O2 - BHO: Skype Control Class - {9018F6A8-2495-45DF-9F16-C738F8F3C8FF} - C:\WINDOWS\system32\SkypeComm.dll
O2 - BHO: Windows Live Sign-in Helper - {9030D464-4C02-4ABF-8ECC-5164760863C6} - C:\Program Files\Common Files\Microsoft Shared\Windows Live\WindowsLiveLogin.dll
O3 - Toolbar: Megaupload Toolbar - {4E7BD74F-2B8D-469E-CCB0-B130EEDBE97C} - C:\PROGRA~1\MEGAUP~1\MEGAUP~1.DLL
O3 - Toolbar: (no name) - {E0E899AB-F487-11D5-8D29-0050BA6940E3} - (no file)
O4 - HKLM\..\Run: [S3Trayp] S3trayp.exe
O4 - HKLM\..\Run: [IMJPMIG8.1] C:\WINDOWS\IME\imjp8_1\IMJPMIG.EXE /Spoil /RemAdvDef /Migration32
O4 - HKLM\..\Run: [MSPY2002] C:\WINDOWS\System32\IME\PINTLGNT\ImScInst.exe /SYNC
O4 - HKLM\..\Run: [PHIME2002ASync] C:\WINDOWS\System32\IME\TINTLGNT\TINTSETP.EXE /SYNC
O4 - HKLM\..\Run: [PHIME2002A] C:\WINDOWS\System32\IME\TINTLGNT\TINTSETP.EXE /IMEName
O4 - HKLM\..\Run: [HDAudDeck] C:\Program Files\VIA\VIAudioi\HDADeck\HDeck.exe 1
O4 - HKLM\..\Run: [ATICCC] "C:\Program Files\ATI Technologies\ATI.ACE\CLIStart.exe"
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\QTTask.exe" -atboottime
O4 - HKLM\..\Run: [AppleSyncNotifier] C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleSyncNotifier.exe
O4 - HKLM\..\Run: [iTunesHelper] "C:\Program Files\iTunes\iTunesHelper.exe"
O4 - HKLM\..\Run: [KernelFaultCheck] %systemroot%\system32\dumprep 0 -k
O4 - HKCU\..\Run: [msnmsgr] "C:\Program Files\Windows Live\Messenger\MsnMsgr.Exe" /background
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - Global Startup: Adobe Gamma Loader.lnk = C:\Program Files\Common Files\Adobe\Calibration\Adobe Gamma Loader.exe
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\OFFICE11\EXCEL.EXE/3000
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_05\bin\ssv.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_05\bin\ssv.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~2\OFFICE11\REFIEBAR.DLL
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O12 - Plugin for .spop: C:\Program Files\Internet Explorer\Plugins\NPDocBox.dll
O16 - DPF: {0E5F0222-96B9-11D3-8997-00104BD12D94} (PCPitstop Utility) - http://www.pcpitstop.com/pcpitstop/pcpitstop.cab
O16 - DPF: {3EA4FA88-E0BE-419A-A732-9B79B87A6ED0} (CTVUAxCtrl Object) - http://dl.tvunetworks.com/TVUAx.cab
O16 - DPF: {4BFD075D-C36E-4F28-BB0A-5D472795197A} (PowerLoader Class) - http://www.powerchallenge.com/applet/PowerLoader.cab
O16 - DPF: {4F1E5B1A-2A80-42CA-8532-2D05CB959537} (MSN Photo Upload Tool) - http://gfx1.hotmail.com/mail/w2/resources/MSNPUpld.cab
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) - http://www.update.microsoft.com/windowsupd...b?1187932241421
O16 - DPF: {67A5F8DC-1A4B-4D66-9F24-A704AD929EEE} (System Requirements Lab) - http://www.nvidia.com/content/DriverDownlo.../sysreqlab2.cab
O16 - DPF: {67DABFBF-D0AB-41FA-9C46-CC0F21721616} (DivXBrowserPlugin Object) - http://download.divx.com/player/DivXBrowserPlugin.cab
O16 - DPF: {C3F79A2B-B9B4-4A66-B012-3EE46475B072} (MessengerStatsClient Class) - http://messenger.zone.msn.com/binary/Messe...nt.cab56907.cab
O16 - DPF: {D27CDB6E-AE6D-11CF-96B8-444553540000} (Shockwave Flash Object) - http://fpdownload2.macromedia.com/get/shoc...ash/swflash.cab
O17 - HKLM\System\CCS\Services\Tcpip\..\{CC5395CF-6C54-4123-AFF4-987F0013DC94}: NameServer = 202.156.1.68,202.156.1.48
O17 - HKLM\System\CS1\Services\Tcpip\..\{CC5395CF-6C54-4123-AFF4-987F0013DC94}: NameServer = 202.156.1.68,202.156.1.48
O20 - Winlogon Notify: winwea32 - C:\WINDOWS\SYSTEM32\winwea32.dll
O23 - Service: Apple Mobile Device - Apple Inc. - C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
O23 - Service: Ati HotKey Poller - ATI Technologies Inc. - C:\WINDOWS\system32\Ati2evxx.exe
O23 - Service: ATI Smart - Unknown owner - C:\WINDOWS\system32\ati2sgag.exe
O23 - Service: Bonjour Service - Apple Inc. - C:\Program Files\Bonjour\mDNSResponder.exe
O23 - Service: Creative Service for CDROM Access - Creative Technology Ltd - C:\WINDOWS\system32\CTsvcCDA.EXE
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: ServiceLayer - Nokia. - C:\Program Files\PC Connectivity Solution\ServiceLayer.exe

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End of file - 7557 bytes

In this thread - http://forums.whatthetech.com/Please_check...log_t93291.html - you were advised to install an antivirus program because you didn't have an up-to-date one running. Your log shows neither entries for an anti-virus program nor a third-party software firewall. Given the lack of basic security programs onboard, the best suggestion I can offer is to back up any important files and then reformat and reinstall Windows.
It is going to be impossible to guarantee a clean computer at the end of the removal process, which makes it something of a waste of my time and yours to start it in the first place. The possibility that legitimate files may have been infected or corrupted by the malware present on your PC, and also that security settings may have been lowered making your computer more liable to infection in the future, means that starting over is the easiest and most reliable solution to your problems.
You also need to be aware of the risk of identity theft if you have accessed bank accounts with this computer or shopped online. Keylogging software could have recorded details of these actions and a lack of an effective firewall means that there is nothing to stop this information being sent home. If this does apply to you, i'd monitor your accounts and perhaps consider getting credit/debit cards, passwords etc... changed - obviously not using this PC!

There are a few free firewalls available.
Comodo Firewall Pro, available here.
PC Tools Firewall Plus, available here.
Online Armor Free, available here.

It is important to note that you should only have one firewall installed at a time, but you can download them all to your Desktop and install each in turn to see which one you prefer.

Understanding and Using Firewalls: http://www.bleepingcomputer.com/tutorials/tutorial60.html

Free anti-virus programs.
AVG Free Edition: Available here.
avast! 4 Home Edition: Available here
AntiVir PersonalEdition Classic :Available here

While you can download them all to see which one you prefer, only install one at a time - running two or more anti-virus programs simultaneously can cause conflicts resulting in less, not more, protection.

Ok. Got it. But previous thread was my laptop while currently this is my desktop PC.

PCs are PCs - they all need adequate security programs. The fact that it was a different machine just means that you didn't take the advice onboard.